RNAi therapeutics have shown great success with multiple US Food and Drug Administration (FDA)-approved products involving N-acetyl galactosamine (GalNAc)-conjugated siRNAs to treat liver-targeted ...

The analysis script will compare the distributions of output sequences for 3HG5_A2G over 3HG5_GLA, which are mutations enriched in the non-native substrate (A2G/N-acetyl-galactosamine) over the native ...

The flavonoid silymarin and one of its structural components, silibinin, are substances with documented hepatoprotective properties. Their mechanisms of action are still poorly understood. However ...

In the present study, we analyzed the effect of candida-derived β-glucan pretreatment on acute liver failure induced by lipopolysaccharide (LPS) in D-galactosamine (D-GalN)-sensitized mice. Methods ...

This directory contains scripts related to the manuscript "An ancient deletion in the ABO gene affects the composition of the porcine microbiome by altering intestinal N-acetyl-galactosamine ...

7 The exact chemical structure of the C-polysaccharide has been established as a ribitol teichoic acid containing glucose, 2-acetamido-2,4,6-trideoxygalactose, galactosamine, ribitol phosphate, and ...

Here we introduce a new shorthand nomenclature for designating the disaccharide subunit structure of all glycosaminoglycans as a way to compare compositions and describe linear sequences.

The source text specifies to cook the ingredients in 12 cups [2400 mL] of water until 6 cups [1200 mL] of the liquid remain. Discard the residue and cook the strained decoction again until it is ...

16 The thin-layer chromatography showed a normal pattern of oligosaccharides. Consecutive enzymatic analysis in blood showed normal activity of galactosamine-6-sulfatase and β-galactosidase, thus ...

Les groupes sanguins érythrocytaires sont définis grâce aux différences observées entre les individus à la surface des érythrocytes. Il s’agit donc de caractères allotypiques, c'est-à-dire différents ...

The results of most clinical trials with the thistle (Silybum marianum) extract, silymarin, are difficult to interpret because of a variety of reasons: small sample size, variability in type and ...